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This combination medication is used to treat a wide variety of bacterial infections. It is known as a penicillin-type antibiotic. It works by stopping the growth of bacteria.
This medication is given by injection into a vein, usually every 6 hours or as directed by your doctor. The dosage is based on your medical condition and response to therapy. For children, the dosage is also based on weight.
If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.
Give aminoglycosides (such as gentamicin) separately from this medication. Do not mix together in the same IV fluid.
For the best effect, use this antibiotic at evenly spaced times. To help you remember, use this medication at the same time(s) every day.
Continue to use this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.
Tell your doctor if your condition persists or worsens.
Nausea, vomiting, or diarrhea may occur. If this medication is injected into a muscle, pain at the injection site may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Tell your doctor right away if you have any serious side effects, including: pain/swelling at injection site (if this drug is injected into a vein), chest pain, difficult/painful urination, easy bruising/bleeding, signs of liver disease (such as persistent nausea/vomiting, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine), new signs of infection (such as fever, persistent sore throat).
This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Tell your doctor right away if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.
Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.
Ampicillin can commonly cause a mild rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe allergic reaction. Therefore, get medical help right away if you develop any rash.
Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to penicillin or cephalosporin antibiotics; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: viral infections (e.g., infectious mononucleosis), kidney disease, liver disease (especially if caused by past use of ampicillin/sulbactam).
This medication contains sodium. Consult your doctor or pharmacist if you are on a salt-restricted diet or if you have a condition that could be worsened by an increase in salt intake (e.g., congestive heart failure).
This medication may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.
Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be at greater risk for side effects while using this drug.
This medication passes into breast milk. Consult your doctor before breast-feeding.
Consult the product instructions and your pharmacist for storage details. Keep all medications away from children and pets.
Some products that may interact with this drug include: aminoglycosides (such as gentamicin), "blood thinners" (such as warfarin), methotrexate, tetracyclines.
Although most antibiotics are unlikely to affect hormonal birth control such as pills, patch, or ring, a few antibiotics (such as rifampin, rifabutin) can decrease their effectiveness. This could result in pregnancy. If you use hormonal birth control, ask your doctor or pharmacist for more details.
This medication may interfere with certain laboratory tests (including certain urine glucose tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: seizures.
For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist right away to establish a new dosing schedule. Do not double the dose to catch up.
Laboratory and/or medical tests (e.g., kidney function, complete blood count) may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.