tacrolimus

Tacrolimus is used with other medications to prevent rejection of a kidney, heart, or liver transplant. This medication belongs to a class of drugs known as immunosuppressants. It works by weakening your body's defense system (immune system) to help your body accept the new organ as if it were your own.

Show more
120 Capsules, 1 mg

My Rx is at Blink Pharmacy

Set your location
delivery-truck
Home DeliveryHow it works?

Fast, free delivery from Blink Pharmacy. Our pharmacist can transfer your prescription from your doctor or current pharmacy. Pay with insurance also available in select cities.

Safe Pharmacy logoLegitScript approved
  • Includes medication
  • Free shipping
  • No membership fees
pharmacy
Everyday Low PriceHow it works?

Pick up at any participating pharmacy near you.

Walmart logoAlbertsons logoSafeway logoSee all
  • Local pharmacy pickup
  • 35,000+ pharmacies
Enrolled in a Quick Save Program? Sign in

Lowest Prices

Get the lowest prices on generic medications.

Private and secure

Your privacy is always protected and your information is secure.

Convenience

Choose from our flexible purchasing options to find what's right for you.

Prescriptions made easy

We work with your doctor or local pharmacist to take care of transfers, refill requests, and more.

About tacrolimus

Overview

Tacrolimus is used with other medications to prevent rejection of a kidney, heart, or liver transplant. This medication belongs to a class of drugs known as immunosuppressants. It works by weakening your body's defense system (immune system) to help your body accept the new organ as if it were your own.

How to use

Read the Patient Information Leaflet if available from your pharmacist before you start taking tacrolimus and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food, usually every 12 hours or as directed by your doctor. If you have nausea or an upset stomach, you may take this drug with food, although this may cause your body to absorb less of the drug. However, you must choose one way (with food or without food) and always take this medication the same way so that your body always absorbs the same amount of drug. Consult your doctor or pharmacist for more details.

If you are taking the capsules, swallow them whole. Do not open or crush the capsules.

If you are using the granules, read the manufacturer's Instructions for Use first. Use only non-plastic cups, spoons, or oral syringes when preparing or taking a dose. Do not sprinkle the granules on food. Open up the prescribed number of packets for your dose and mix the granules in a cup with 1 to 2 tablespoons (15 to 30 milliliters) of room temperature water and stir well. Drink the dose immediately. You may use an oral syringe to give the dose. Rinse the cup or syringe with the same amount of water and drink the rinse water to make sure the complete dose is taken. Do not prepare the granule mixture ahead of time. Do not save any of the mixture for later use.

Dosage is based on your weight, medical condition, blood test results (e.g., tacrolimus trough levels), and response to therapy.

Tacrolimus is available in different formulations (such as immediate and extended-release). Do not switch between different forms of tacrolimus without consulting your doctor.

Do not increase your dose or take this medication more often without your doctor's approval. Your condition will not improve any faster and the risk of serious side effects may be increased. Also, do not stop taking this medication without your doctor's approval.

Take this medication regularly in order to get the most benefit from it. It is important to take all doses on time to keep the amount of medicine in your body at a constant level. Remember to take it at the same times each day.

Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for more details.

Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the capsules.

Inform your doctor if your condition worsens.

Side effects

See also Warning section.

Shaking, headache, diarrhea, nausea/vomiting, upset stomach, loss of appetite, trouble sleeping, and numbness/tingling of the hands/feet may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: mental/mood changes, dizziness, signs of kidney problems (such as change in the amount of urine), pounding heartbeat, symptoms of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain), hearing problems (such as hearing loss, ringing in the ears), pain/redness/swelling of arms or legs, easy bruising/bleeding, muscle pain/cramp/weakness, yellowing skin/eyes, dark urine, persistent nausea/vomiting, severe stomach/abdominal pain, severe leg pain.

This medication may also increase your risk of getting a rare but very serious (sometimes fatal) brain infection (progressive multifocal leukoencephalopathy-PML). Get medical help right away if any of these rare but very serious side effects occur: clumsiness, loss of coordination, weakness, sudden change in your thinking (such as confusion, difficulty concentrating), difficulty moving your muscles, problems with speech, seizure, vision changes.

Get medical help right away if you have any very serious side effects, including: fainting, fast/irregular heartbeat, severe dizziness, chest/jaw/left arm pain, black stools, vomit that looks like coffee grounds.

This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high. Your doctor may control your blood pressure with medication.

Tacrolimus may cause diabetes. Tell your doctor or pharmacist if you experience any of the following symptoms of high blood sugar: increased thirst/hunger, frequent urination.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Warnings & Precautions

Before taking tacrolimus, tell your doctor or pharmacist if you are allergic to it; or to other macrolide medications (such as sirolimus); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: mineral imbalances (such as high potassium), kidney disease, any recent/current infections, cancer, liver disease, high blood pressure, diabetes.

Tacrolimus may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using tacrolimus, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).

Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using tacrolimus safely.

This medication may increase your risk of developing skin cancer. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors.

Tacrolimus can make you more likely to get infections or may worsen any current infections. Therefore, wash your hands well to prevent the spread of infection. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.

Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).

This drug may increase your potassium levels. Before using potassium supplements or salt substitutes containing potassium, consult your doctor or pharmacist.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above).

Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the capsules.

Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using tacrolimus. Tacrolimus may harm an unborn baby. Men and women using this medication should ask about reliable forms of birth control before and while using this medication. If you or your partner become pregnant, talk to your doctor right away about the risks and benefits of this medication. Do not stop taking this medication unless directed by your doctor.

This drug passes into breast milk and the effect on a nursing infant is unknown. Discuss the risks and benefits with your doctor before breast-feeding.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Drug interactions

See also How to Use section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: aluminum/magnesium antacid, cyclosporine, sirolimus, temsirolimus, ziprasidone, other drugs that may increase the level of potassium in the blood (such as "water pills" including amiloride, spironolactone), other drugs that weaken the immune system/increase the risk of infection (such as natalizumab, rituximab).

Other medications can affect the removal of tacrolimus from your body, which may affect how tacrolimus works. Examples include cimetidine, danazol, nefazodone, ethinyl estradiol, methylprednisolone, St. John's wort, azole antifungals (such as itraconazole, voriconazole), HIV and HCV protease inhibitors (such as nelfinavir, ritonavir, boceprevir, telaprevir), rifamycins (such as rifampin, rifabutin), certain anti-seizure drugs (such as phenobarbital, phenytoin), among others.

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

More

Missed Doses:

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Notes:

Laboratory and/or medical tests (e.g., potassium levels, blood pressure, blood sugar, tacrolimus trough level, kidney/liver function) will be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

If you have had an organ transplant, it is recommended that you attend a transplant education class or support group. Learn the signs of organ rejection such as a feeling of being ill, fever, or tenderness/pain around the transplanted organ. Tell your doctor right away if you notice any of these signs.

Selected from the Licensed Solutions data included with permission and copyrighted by FDB, inc., 2014. This copyrighted material has been downloaded and Licensed data provider and is not for distribution in professional healthcare settings. This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking any drug or commencing or discontinuing any course of treatment. 

Frequently Asked Questions

What is Blink Health?

Blink Health is driving down the cost of prescription drugs in America with up to 80% savings on prescription medications. Pay our discounted price online and receive free home delivery from our licensed US pharmacy or pickup at any of our 35,000+ participating pharmacies nationwide. There are no membership fees and prescription transfers are easy.

Looking to pay with Blink Pharmacy Plus? Click here.

How do I use Blink for the first time?

To use Blink, you must have a valid prescription from a doctor. Search for your medication on blinkhealth.com and pay online.

For free home delivery, we can help transfer prescriptions from your doctor or current pharmacy during checkout. Once we've received your prescription, your medication will be delivered in 4-6 business days.

For local pharmacy pickup, pay online and you will receive a Blink card. Go to any of our participating pharmacies, show your Blink card to the pharmacist and pay $0 at the counter. Make sure the pharmacy has your prescription from your doctor.

Prefer to get start over the phone give us a call 1 (833) 844 - 9621.

If you don't have a prescription or need to renew your prescription, we can connect you with a US licensed medical professional for an online doctor visit for E.D., hair loss, birth control, cold sores, acid reflux, and high cholesterol.

Do I need a prescription?

Yes, you need a valid prescription from a doctor to use Blink.

If you don't have a prescription, we can connect you with a licensed medical professional for an online doctor visit for E.D., hair loss, birth control, cold sores, acid reflux, and high cholesterol.

Does my pharmacy accept Blink?

Blink is accepted at 35,000+ pharmacies nationwide, including Walmart, Albertsons, Kroger, Publix, Costco, Safeway, HEB, Brookshires, and many more. Most independent pharmacies also accept Blink. Find a pharmacy near you here.

Need help?

Our patient support team is available Monday through Friday 8AM - 10PM EST, and Saturday and Sunday 9AM - 7PM EST.

info@blinkhealth.com1 (844) 265-6444
Mon–Fri: 8 am–10 pm ETSat–Sun: 9 am–7 pm ET
Blink Health is driving down the cost of prescription drugs for everyone in America.


Blink Health is driving down the cost of prescription drugs for everyone in America.Try the app now

Open Accessibility Helper

Blink Health is NOT insurance. The discount plan organization is Blink Health Administration LLC, 1407 Broadway, Suite 1910, New York, NY 10018, 1 (844) 265-6444, www.blinkhealth.com.