Leuprolide is used to treat disorders of the uterus (such as endometriosis, fibroids). For the treatment of fibroids, leuprolide is usually given with iron to help improve anemia that is caused by too much vaginal bleeding. Leuprolide helps to reduce symptoms such as pelvic pain, painful/heavy menstrual periods, and abdominal bloating. It works by shrinking the abnormal uterine tissue that causes these symptoms. Uterine tissue needs the female hormone estrogen to grow and spread. Leuprolide helps to decrease the amount of estrogen that is made in the body.
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