See also Warning section.
Headache, fever, chills, flushing, mild rash/itching, nausea, vomiting, shortness of breath, tiredness, or dizziness may occur during or after the infusion. Tell your doctor or pharmacist right away if any of these effects occur. Your doctor may prescribe additional medications to help control these symptoms. Diarrhea, stomach/abdominal pain, cough, trouble sleeping, or mouth sores may also occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
People using this medication may have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.
Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as depression, anxiety), muscle/bone/back pain, signs of thyroid disease (such as unusual weight changes, increased sweating, constipation, feeling cold, fast/slow/irregular heartbeat), signs of liver disease (such as nausea/vomiting that doesn't stop, loss of appetite, severe stomach/abdominal pain, yellowing eyes/skin, dark urine).
This medication may increase your risk of getting a rare but very serious (possibly fatal) brain infection (progressive multifocal leukoencephalopathy-PML). Get medical help right away if you have any of these side effects: clumsiness, loss of coordination/balance, weakness, sudden change in your thinking (such as confusion, difficulty concentrating, memory loss), difficulty talking/walking, seizure, vision changes.
Get medical help right away if you have any very serious side effects, including: fainting, chest/jaw/left arm pain.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.