See also How to Use section.
Tiredness, loss of appetite, nausea, constipation, muscle/bone pain, or swelling hands/ankles/feet may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
People using this medication may have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.
Tell your doctor right away if you have any serious side effects, including: signs of liver disease (such as nausea/vomiting that doesn't stop, stomach/abdominal pain, yellowing eyes/skin, dark urine), new/worsening cough, diarrhea, blood/mucus in your stool, eye/vision problems (such as blurred vision, vision changes, eye pain), headache that is severe or doesn't go away, stiff/painful neck, unusual weight gain/loss, mental/mood changes (such as confusion), cold or heat intolerance, fast/slow/pounding/irregular heartbeat, increased thirst/urination, muscle weakness, easy bruising/bleeding, signs of kidney problems (such as pink/bloody urine, change in the amount of urine).
Get medical help right away if you have any very serious side effects, including: chest pain, shortness of breath.
This medication may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as sore throat that doesn't go away, fever, chills, burning/painful/urgent urination).
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.