bosentan

Bosentan is used to treat high blood pressure in the lungs (pulmonary arterial hypertension). This condition is thought to be caused by increased levels of a certain natural substance (endothelin-1). This medication blocks the effects of endothelin-1, thereby helping to decrease the blood pressure in the lungs, slow the worsening of symptoms from the disease, and improve your ability to exercise.

Show more
30 Tablets, 62.5 mg

My Rx is at Blink Pharmacy

Set your location
pharmacy
Everyday Low PriceHow it works?

Pick up at any participating pharmacy near you.

Walmart logoAlbertsons logoSafeway logoSee all
  • Local pharmacy pickup
  • 35,000+ pharmacies
Enrolled in a Quick Save Program? Sign in

Lowest Prices

Get the lowest prices on generic medications.

Private and secure

Your privacy is always protected and your information is secure.

Prescriptions made easy

We work with your doctor or local pharmacist to take care of transfers, refill requests, and more.

About bosentan

Overview

Bosentan is used to treat high blood pressure in the lungs (pulmonary arterial hypertension). This condition is thought to be caused by increased levels of a certain natural substance (endothelin-1). This medication blocks the effects of endothelin-1, thereby helping to decrease the blood pressure in the lungs, slow the worsening of symptoms from the disease, and improve your ability to exercise.

How to use

Read the Medication Guide provided by your pharmacist before you start using bosentan and each time you get a refill. If you have any questions, consult your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually twice daily (in the morning and evening).

The dosage is based on your medical condition, weight, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor may start you on a lower dose of this medication and then increase the dose after several weeks.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.

Women who are pregnant or who may become pregnant should not handle the tablets or breathe the dust from this medication. Do not crush the tablets because doing so will increase exposure to the dust.

Tell your doctor if your condition persists or worsens.

Side effects

See also Warning section.

Dizziness, flushing, stuffy nose, or joint pain may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: fast/pounding heartbeat, unusual tiredness, swelling ankles/feet, unusual/sudden weight gain, fainting, shortness of breath, coughing up blood.

In men, this medication can decrease sperm production, which may affect the ability to father a child. Talk to your doctor for more details.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever, swollen lymph nodes, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Warnings & Precautions

See also Warning section.

Before taking bosentan, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, anemia.

This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). Alcohol may also increase the risk of serious liver problems.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This medication must not be used during pregnancy. It may harm an unborn baby. Therefore, it is important to prevent pregnancy while using this medication. Discuss the use of at least two reliable forms of birth control (such as condoms, birth control pills) with your doctor. If you become pregnant or think you may be pregnant, tell your doctor right away.

It is not known whether this medication passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Drug interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Other medications can affect the removal of bosentan from your body, which may affect how bosentan works. Examples include cyclosporine, HIV protease inhibitors (such as atazanavir), among others.

This drug can speed up the removal of other drugs from your body, which may affect how they work. Examples of affected drugs include glyburide, certain products used to treat chronic hepatitis C (asunaprevir, ombitasvir/paritaprevir/ritonavir), among others.

This medication may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. Discuss with your doctor or pharmacist about using an additional reliable birth control method while using this medication. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well.

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe headache, severe dizziness, nausea, vomiting.

More

Missed Doses:

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

Notes:

Do not share this medication with others.

Laboratory and/or medical tests (such as liver function tests, pregnancy tests, hemoglobin, hematocrit) should be performed before you start treatment, and periodically to monitor your progress or check for side effects. Consult your doctor for more details.

Selected from the Licensed Solutions data included with permission and copyrighted by FDB, inc., 2014. This copyrighted material has been downloaded and Licensed data provider and is not for distribution in professional healthcare settings. This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking any drug or commencing or discontinuing any course of treatment. 

Frequently Asked Questions

What is Blink Health?

Blink Health is driving down the cost of prescription drugs in America with up to 80% savings on prescription medications. Pay our discounted price online and receive free home delivery from our licensed US pharmacy or pickup at any of our 35,000+ participating pharmacies nationwide. There are no membership fees and prescription transfers are easy.

Looking to pay with BlinkRx? Click here.

How do I use Blink for the first time?

To use Blink, you must have a valid prescription from a doctor. Search for your medication on blinkhealth.com and pay online.

For free home delivery, we can help transfer prescriptions from your doctor or current pharmacy during checkout. Once we've received your prescription, your medication will be delivered in 4-6 business days.

For local pharmacy pickup, pay online and you will receive a Blink card. Go to any of our participating pharmacies, show your Blink card to the pharmacist and pay $0 at the counter. Make sure the pharmacy has your prescription from your doctor.

Prefer to get start over the phone give us a call 1 (833) 844 - 9621.

If you don't have a prescription or need to renew your prescription, we can connect you with a US licensed medical professional for an online doctor visit for E.D., hair loss, birth control, cold sores, acid reflux, and high cholesterol.

Do I need a prescription?

Yes, you need a valid prescription from a doctor to use Blink.

If you don't have a prescription, we can connect you with a licensed medical professional for an online doctor visit for E.D., hair loss, birth control, cold sores, acid reflux, and high cholesterol.

Does my pharmacy accept Blink?

Blink is accepted at 35,000+ pharmacies nationwide, including Walmart, Albertsons, Kroger, Publix, Costco, Safeway, HEB, Brookshires, and many more. Most independent pharmacies also accept Blink. Find a pharmacy near you here.

Need help?

Our patient support team is available Monday through Friday 8AM - 10PM EST, and Saturday and Sunday 9AM - 7PM EST.

info@blinkhealth.com1 (844) 265-6444
Mon–Fri: 8 am–10 pm ETSat–Sun: 9 am–7 pm ET
Blink Health is driving down the cost of prescription drugs for everyone in America.


Blink Health is driving down the cost of prescription drugs for everyone in America.Try the app now

Open Accessibility Helper

Blink Health is NOT insurance. The discount plan organization is Blink Health Administration LLC, 1407 Broadway, Suite 1910, New York, NY 10018, 1 (844) 265-6444, www.blinkhealth.com.